One in five people in the United States will have a sexually transmitted infection in a given year, with nearly 68 million infections in 2018. STIs are often asymptomatic (especially in women) and are therefore often undiagnosed and unreported. Untreated STIs can have severe health consequences, including chronic pelvic pain, infertility, miscarriage or newborn death, and increased risk of HIV infection, genital and oral cancers, neurological and rheumatological effects. In light of this, the Centers for Disease Control and Prevention, through the National Association of County and City Health Officials, commissioned the National Academies of Sciences, Engineering, and Medicine to convene a committee to examine the prevention and control of sexually transmitted infections in the United States and provide recommendations for action.Members of the committee who wrote the report, Sexually Transmitted Infections: Adopting a Sexual Health Paradigm, will give an overview of key issues, conclusions and recommendations.